Evidenced Based Management: A Journey for Physicians
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Historical Perspective, Epidemiology, and Methodology
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Overview of the SCD guidelines and chapters
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Process and methodology
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Consensus Statements
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Clinical Practice Guidelines and the institute of Medicine
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Prevention of invasive infection
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Screening for Renal Disease
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Electrocardiogram Screening
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Screening for hypertension
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Screening for Retinopathy
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Screening for risk of stroke using neuroimaging
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Screening for Pulmonary disease
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Reproductive counseling
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Contraception
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Clinical Preventive services
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Immunizations
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Vaso-Occlusive Crisis
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Fever
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Acute Renal Failure
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Priapism
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Hepatobiliary Complications
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Acute Anemia
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Splenic Sequestration
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Acute Chest Syndrome
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Acute Stroke
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Multisystem Organ Failure
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Acute Ocular Conditions
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Chronic pain
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Avascular Necrosis
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Leg Ulcers
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Pulmonary Hypertension
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Renal Complications
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Stuttering/Recurrent Priapism
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Ophthalmologic Complications
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Summary of the Evidence
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Hydroxurea Treatment Recommendations
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Consensus Treatment Protocol and Technical remarks for the implementation of Hydroxyurea Therapy
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Indications for transfusions
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Recommendations for Acute and Chronic Transfusion Therapy
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Appropriate Management/ Monitoring
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Consensus Protocol for Monitoring Individuals on Chronic Transfusion Therapy
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Complications of Transfusions
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Recommendations for the Management and Prevention of Transfusion Complications
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New Research is Needed
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Data Systems That Meet the Highest Standards of Scientific Rigor Can Be Invaluable
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Improved Phenotyping is needed
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Broad collaborations for Research and Care
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Beyond Efficacy
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Look, Listen, Empathize and Ask
Recommendations for Acute and Chronic Transfusion Therapy
SCFA_Coach September 25, 2023
Exhibits 14-19 summarize the expert panel’s recommendations for transfusion therapy in acute and chronic complications. A more detailed discussion of the indications for transfusion and the evidence to support these recommendations for each disorder can be found in the chapters on health maintenance, acute complications,or chronic complications. Exhibits 14-19 are designated as either graded or consensus recommendations.
Exhibit 14. Acute Complications-Graded Recommendations To Transfuse
Exhibit 15. Acute Complications-Consensus Recommendations To Transfuse
Exhibit 16. Acute Complications-Graded Recommendations When Transfusion Is Not Indicated
Exhibit 17. Acute Complications-Consensus Recommendations When Transfusion Is Not Indicated
Exhibit 18. Chronic Complications-Graded Recommendations for When To Initiate a Chronic Transfusion Program
Exhibit 19. Chronic Complications-Graded Recommendations for When Transfusion is Not Indicated