360° SCD Hub
360° SCD Hub

Lesson Category: Chapter 5: Hydroxyrea Therapy

Summary of the Evidence

A comprehensive systematic review was conducted evaluating the efficacy, effectiveness, harms, and barriers associated with using hydroxyurea in SCD. Three randomized trials and 54 observational…

Hydroxurea Treatment Recommendations

Recommendations Educate all patients with SCA and their family members about hydroxyurea therapy. (See consensus treatment protocol on page 145). (Consensus-Panel Expertise) In adults with…

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